CosMx™ Mouse Neuroscience Panel
みなさまの研究の一助に
マウスシングルセル空間RNA解析
CosMx Mouse Neuroscience Panel は、マウスの脳やその他の神経組織において、堅牢な細胞タイピング、細胞間相互作用解析などを提供するように設計されています。 高度に精選された1000のターゲットの発現をサブセルラーの解像度でプロファイルし、最大 50 の独自のターゲットでのカスタマイズができます。
論文&ポスター
Characterizing Late-Onset AD Models Using Spatial Whole Transcriptome Analysis – AGBT 2021
Smarca4-deficient lung cancers display a metastatic-like cell state and a distinct cell-of-origin – AGBT 2021
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18-SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer-immune interplay in SyS using an integrative approach that combines single-cell RNA sequencing (scRNA-seq), spatial profiling and genetic and pharmacological perturbations.
The spatial landscape of lung pathology during COVID-19 progression
Recent studies have provided insights into the pathology and immune response to coronavirus disease 2019 (COVID-19)1–8. However, thorough interrogation of the interplay between infected cells and the immune system at sites of infection is lacking.
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection
The relationship of SARS-CoV-2 pulmonary infection and severity of disease is not fully understood. Here we show analysis of autopsy specimens from 24 patients who succumbed to SARS-CoV-2 infection using a combination of different RNA and protein analytical platforms to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection.
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